The potential harms of sedentary behaviour on cardiometabolic health are mitigated in highly active adults: a compositional data analysis

Table 4 Multiple linear regression analyses of the relationship between isometric log-ratio (ilr) coordinates of sedentary time and MVPA and cardiometabolic health related outcomes

	ILR/ln(sedentary time: other behaviours)				ILR/ln(MVPA: other behaviours)
	r²	B	SE	p-value	r²	B	SE	p-value
Waist circumference^a	0.450	− 0.015	0.017	0.373	0.447	− 0.008	0.011	0.455
Systolic blood pressure	0.452	4.663	4.004	0.249	0.444	− 1.814	2.646	0.496
Diastolic blood pressure	0.318	4.252	2.654	0.313	0.282	− 3.161	2.144	0.146
Fat mass percentage^a	0.499	0.062	0.055	0.262	0.492	− 0.025	0.036	0.481
Oxygen uptake per kg	0.492	− 9.191	3.504	0.011	0.544	8.074	2.178	< 0.001
Fasting glucose	0.160	0.024	0.167	0.885	0.164	− 0.057	0.109	0.603
Glucose 120 min	0.185	0.806	0.603	0.187	0.206	− 0.707	0.394	0.078
Fasting insulin	0.033	− 10.592	18.37	0.567	0.028	1.579	12.078	0.896
Insulin 120 min	0.314	79.04	44.32	0.080	0.327	− 60.27	29.04	0.043
Matsuda index	0.151	− 0.641	1.621	0.694	0.150	0.351	1.023	0.733
IGI	0.094	240.6	111.4	0.422	0.081	− 144.3	73.55	0.055
HOMA-IR	0.142	− 0.031	0.100	0.756	0.141	0.006	0.065	0.931
HOMA-B	0.150	− 0.103	0.096	0.288	0.139	0.041	0.062	0.510
mISI	0.155	− 0.112	0.091	0.227	0.135	0.034	0.062	0.583
HIRI	0.150	8.775	3.173	0.008	0.110	− 4.708	2.128	0.031
tAUC insulin	0.222	0.054	0.014	0.134	0.201	− 0.085	0.044	0.061
tAUC glucose	0.157	63.58	60.46	0.298	0.149	− 31.45	40.18	0.437
Total cholesterol	0.321	0.396	0.301	0.194	0.322	− 0.268	0.197	0.180
Triglycerides	0.058	0.136	0.116	0.247	0.128	− 0.177	0.073	0.019
HDL-cholesterol^a	0.273	0.062	0.046	0.186	0.273	0.04	0.03	0.182
LDL-cholesterol	0.278	0.105	0.267	0.697	0.320	− 0.317	0.17	0.068
CCMS	0.374	0.099	0.228	0.667	0.412	− 0.311	0.154	0.094

All models were adjusted for sex, age, smoking status, chronic disease and medication. B unstandardised beta coefficients, HIRI hepatic insulin resistance index, HDL high-density lipoprotein, HOMA-B homeostatic model assessment of β-cell function, HOMA-IR homeostatic model assessment of insulin resistance, ILR isometric log-ratio, IGI insulinogenic index, kg kilogram, LDL low-density lipoprotein, mISI muscle insulin sensitivity index, MVPA moderate-to-vigorous physical activity, SE standard error, tAUC total area under curve, CCMS clustered cardiometabolic risk score. Significant associations are shown in bold
^aVariables were log-transformed due to the abnormal distribution of the data

ISSN: 2731-4391